FOXC1 Rabbit Polyclonal Antibody

CAT#: TA330238

Rabbit Polyclonal Anti-FOXC1 Antibody

Product Images

WB Suggested Anti-FOXC1 Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-FOXC1 antibody: synthetic peptide directed towards the C terminal of human FOXC1. Synthetic peptide located within the following region: GERGGHLQGAPGGAGGSAVDNPLPDYSLPPVTSSSSSSLSHGGGGGGGGG
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: forkhead box C1
• Database Link:
  NP_001444
  Entrez Gene 2296 Human
  UniProt ID Q12948
• Background: FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
• Synonyms: ARA; FKHL7; FREAC-3; FREAC3; IGDA; IHG1; IRID1; RIEG3
• Note: Immunogen sequence homology: Human: 93%; Rat: 86%; Mouse: 86%

Reference Data

• Protein Families: Druggable Genome, Transcription Factors