DIABLO Rabbit Polyclonal Antibody

CAT#: TA330330

Rabbit Polyclonal Anti-DIABLO Antibody

Product Images

WB Suggested Anti-DIABLO Antibody Titration: 0.3125 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-DIABLO antibody: synthetic peptide directed towards the C terminal of human DIABLO. Synthetic peptide located within the following region: LVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 21 kDa
• Gene Name: diablo IAP-binding mitochondrial protein
• Database Link:
  NP_620308
  Entrez Gene 56616 Human
  UniProt ID Q9NR28
• Background: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
• Synonyms: DFNA64; SMAC
• Note: Immunogen sequence homology: Human: 100%; Dog: 92%; Bovine: 85%; Horse: 85%; Pig: 85%

Reference Data

• Protein Families: Transmembrane