ITCH Rabbit Polyclonal Antibody

CAT#: TA330480

Rabbit Polyclonal Anti-ITCH Antibody


USD 375.00

5 Days*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-ITCH antibody: synthetic peptide directed towards the N terminal of human ITCH. Synthetic peptide located within the following region: QLESEVVTNGETTCSESASQNDDGSRSKDETRVSTNGSDDPEDAGAGENR
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Note that this product is shipped as lyophilized powder to China customers.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 99 kDa
Gene Name itchy E3 ubiquitin protein ligase
Background This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Synonyms ADMFD; AIF4; AIP4; dJ468O1.1; NAPP1
Note Immunogen sequence homology: Human: 100%; Pig: 93%; Rabbit: 93%; Guinea pig: 93%; Dog: 92%; Rat: 86%; Horse: 86%; Bovine: 86%
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Endocytosis, Ubiquitin mediated proteolysis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.