Aprataxin Rabbit Polyclonal Antibody

CAT#: TA331579

Rabbit Polyclonal Anti-APTX Antibody

Product Images

WB Suggested Anti-APTX Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Muscle

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  Host: Rabbit; Target Name: APTX; Sample Tissue: Human HepG2; Antibody Dilution: 1.0ug/ml; APTX is supported by BioGPS gene expression data to be expressed in HepG2

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  Host: Rabbit; Target Name: APTX; Sample Tissue: Human 293T; Antibody Dilution: 1.0ug/ml; APTX is supported by BioGPS gene expression data to be expressed in HEK293T

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-APTX Antibody: synthetic peptide directed towards the middle region of human APTX. Synthetic peptide located within the following region: YPYIVEFEEEAKNPGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSN
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Database Link:
  NP_778241
  Entrez Gene 54840 Human
• Background: APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
• Synonyms: AOA; AOA1; aprataxin; ataxia 1; AXA1; EAOH; early onset with hypoalbuminemia; EOAHA; FHA-HIT; FLJ20157; MGC1072; OTTHUMP00000021188
• Note: Immunogen sequence homology: Human: 100%; Horse: 92%; Dog: 86%; Rabbit: 86%; Pig: 79%; Guinea pig: 79%; Bovine: 77%

Reference Data

• Protein Families: Druggable Genome