PCNA Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human proliferating cell nuclear antigen (PCNA), transcript variant 1
USD 823.00
Transient overexpression lysate of proliferating cell nuclear antigen (PCNA), transcript variant 1
USD 396.00
Other products for "PCNA"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB 1:500 - 1:2000 |
Reactivities | Human, Mouse, Rat, Monkey |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PCNA |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 261 |
Gene Name | proliferating cell nuclear antigen |
Database Link | |
Background | Proliferating cell nuclear antigen (PCNA) is a member of the DNA sliding clamp family of proteins that assist in DNA replication (1). Crystal structure data suggests that a PCNA homotrimer ring can encircle and slide along the DNA double helix (2). Multiple proteins involved in DNA replication, DNA repair, and cell cycle control bind to PCNA rather than directly associating with DNA, thus facilitating fast processing of DNA (reviewed in 3). PCNA protein expression is a well-accepted marker of proliferation and PCNA (PC10) Mouse mAb has been used to assess PCNA levels in hundreds of scientific studies. |
Synonyms | ATLD2 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair |
Documents
Product Manuals |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.