NDUFS5 Rabbit Polyclonal Antibody

CAT#: TA332396

Rabbit anti-NDUFS5 Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse liver tissue lines, using NDUFS5 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human NDUFS5
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 106
• Gene Name: NADH:ubiquinone oxidoreductase subunit S5
• Database Link:
  NP_004543
  Entrez Gene 362588 RatEntrez Gene 595136 MouseEntrez Gene 4725 Human
  UniProt ID O43920
• Background: NDUFS5 gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. The NDUFS5 mRNA is expressed ubiquitously in human tissues, with a relative higher expression in human heart, skeletal muscle, liver, kidney and fetal heart (PMID: 10070614). The NDUFS5 (15 kDa) subunit located at mitochondrion and contains two C-X9-C motifs that are predicted to form a helix-coil-helix structure, permitting the formation of intramolecular disulfide bonds (PMID: 21310150). Proteinteachâ??s NDUFS5 antibody 15224-1-AP is capable of detecting the 15 kDa protein in Western blotting.
• Synonyms: CI-15k; CI15K

Reference Data

• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease