CDK9 Rabbit Polyclonal Antibody

CAT#: TA332408

Rabbit anti-CDK9 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CDK9 antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:1000 - 1:5000
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43kDa
• Gene Name: cyclin-dependent kinase 9
• Database Link:
  NP_001252
  Entrez Gene 107951 MouseEntrez Gene 362110 RatEntrez Gene 1025 Human
  UniProt ID P50750
• Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
• Synonyms: C-2k; CDC2L4; CTK1; PITALRE; TAK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors