Cathepsin D (CTSD) Rabbit Polyclonal Antibody

CAT#: TA332411

Rabbit anti-CTSD Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CTSD antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant Protein of human CTSD
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: cathepsin D
• Database Link:
  NP_001900
  Entrez Gene 13033 MouseEntrez Gene 1509 Human
  UniProt ID P07339
• Background: This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
• Synonyms: CLN10; CPSD; HEL-S-130P

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome