CD151 Rabbit Polyclonal Antibody

CAT#: TA332464

Rabbit anti-CD151 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CD151 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CD151
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 253
• Gene Name: CD151 molecule (Raph blood group)
• Database Link:
  NP_620599
  Entrez Gene 12476 MouseEntrez Gene 64315 RatEntrez Gene 977 Human
  UniProt ID P48509
• Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
• Synonyms: GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24

Reference Data

• Protein Families: Druggable Genome, Transmembrane