Angiopoietin like 4 (ANGPTL4) Rabbit Polyclonal Antibody

CAT#: TA332498

Rabbit anti-ANGPTL4 Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse skeletal muscle, using ANGPTL4 antibody.

• 

  Immunohistochemistry of paraffin-embedded rat lung using ANGPTL4 antibody at dilution of 1:100 (200x lens).

• 

  Immunohistochemistry of paraffin-embedded human esophageal cancer using ANGPTL4 antibody at dilution of 1:100 (200x lens).

• 

  Immunofluorescence analysis of A549 cell using ANGPTL4 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ANGPTL4
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: angiopoietin like 4
• Database Link:
  NP_647475
  Entrez Gene 57875 MouseEntrez Gene 362850 RatEntrez Gene 51129 Human
  UniProt ID Q9BY76
• Background: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
• Synonyms: ANGPTL2; ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: PPAR signaling pathway