N WASP (WASL) Rabbit Polyclonal Antibody

CAT#: TA332562

Rabbit anti-WASL Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using WASL antibody.

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  Immunohistochemistry of paraffin-embedded rat lung using WASL antibody at dilution of 1:100 (400x lens).

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  Immunohistochemistry of paraffin-embedded rat spleen using WASL antibody at dilution of 1:100 (400x lens).

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  Immunofluorescence analysis of U2OS cell using WASL antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human WASL
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 505
• Gene Name: Wiskott-Aldrich syndrome like
• Database Link:
  NP_003932
  Entrez Gene 73178 MouseEntrez Gene 682507 RatEntrez Gene 8976 Human
  UniProt ID O00401
• Background: This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.
• Synonyms: N-WASP; NWASP; WASPB

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton