EIF4A1 Rabbit Polyclonal Antibody

CAT#: TA332587

Rabbit anti-EIF4A1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using EIF4A1 antibody.

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  Immunofluorescence analysis of MCF-7 cell using EIF4A1 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IP, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human EIF4A1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: eukaryotic translation initiation factor 4A1
• Database Link:
  NP_001407
  Entrez Gene 13681 MouseEntrez Gene 287436 RatEntrez Gene 1973 Human
  UniProt ID P60842
• Background: EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
• Synonyms: DDX2A; EIF-4A; eIF-4A-I; EIF4A; eIF4A-I