D Amino Acid Oxidase (DAO) Rabbit Polyclonal Antibody

CAT#: TA332602

Rabbit anti-DAO Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using DAO antibody.

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  Immunofluorescence analysis of MCF-7 cell using DAO antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human DAO
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 347
• Gene Name: D-amino-acid oxidase
• Database Link:
  NP_001908
  Entrez Gene 13142 MouseEntrez Gene 114027 RatEntrez Gene 1610 Human
  UniProt ID P14920
• Background: This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
• Synonyms: DAAO; DAMOX; OXDA

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, D-Arginine and D-ornithine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways