Plasma Kallikrein 1B (KLKB1) Rabbit Polyclonal Antibody

CAT#: TA332607

Rabbit anti-KLKB1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using KLKB1 antibody.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB,1:500 - 1:1000
  IHC-P,1:50 - 1:200
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 71kDa
• Gene Name: kallikrein B1
• Database Link:
  NP_000883
  Entrez Gene 16621 MouseEntrez Gene 25048 RatEntrez Gene 3818 Human
  UniProt ID P03952
• Background: This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: KLK3; PPK

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades