GHRH Rabbit Polyclonal Antibody

CAT#: TA332622

Rabbit anti-GHRH Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using GHRH antibody.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human GHRH
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: growth hormone releasing hormone
• Database Link:
  NP_066567
  Entrez Gene 14601 MouseEntrez Gene 29446 RatEntrez Gene 2691 Human
  UniProt ID P01286
• Background: The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
• Synonyms: GHRF; GRF; INN

Reference Data

• Protein Families: Druggable Genome, Secreted Protein