Syntenin (SDCBP) Rabbit Polyclonal Antibody

CAT#: TA332638

Rabbit anti-SDCBP Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using SDCBP antibody.

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  Immunofluorescence analysis of U2OS cell using SDCBP antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human SDCBP
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 298
• Gene Name: syndecan binding protein
• Database Link:
  NP_005616
  Entrez Gene 6386 Human
  UniProt ID O00560
• Background: The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: MDA-9; MDA9; ST1; SYCL; TACIP18

Reference Data

• Protein Families: Druggable Genome, Transmembrane