Caldesmon (CALD1) Rabbit Polyclonal Antibody

CAT#: TA332644

Rabbit anti-CALD1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CALD1 antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:500 - 1:2000
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 93kDa
• Gene Name: caldesmon 1
• Database Link:
  NP_149130
  Entrez Gene 800 Human
  UniProt ID Q05682
• Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
• Synonyms: CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22

Reference Data

• Protein Pathways: Vascular smooth muscle contraction