EED Rabbit Polyclonal Antibody

CAT#: TA332649

Rabbit anti-EED Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using EED antibody.

Specifications

Product Data

• Applications: ICC/IF, IP, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human EED
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: embryonic ectoderm development
• Database Link:
  NP_003788
  Entrez Gene 13626 MouseEntrez Gene 293104 RatEntrez Gene 8726 Human
  UniProt ID O75530
• Background: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
• Synonyms: HEED; WAIT1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors