EBP1 (PA2G4) Rabbit Polyclonal Antibody

CAT#: TA332652

Rabbit anti-PA2G4 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using PA2G4 antibody.

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  Immunohistochemistry of paraffin-embedded rat heart using PA2G4 antibody at dilution of 1:100 (x400 lens).

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  Immunohistochemistry of paraffin-embedded human liver cancer using PA2G4 antibody at dilution of 1:100 (x400 lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human PA2G4
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: proliferation-associated 2G4
• Database Link:
  NP_006182
  Entrez Gene 18813 MouseEntrez Gene 288778 RatEntrez Gene 5036 Human
  UniProt ID Q9UQ80
• Background: This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
• Synonyms: EBP1; HG4-1; p38-2G4

Reference Data

• Protein Families: Druggable Genome, Protease, Stem cell - Pluripotency