Lipoamide Dehydrogenase (DLD) Rabbit Polyclonal Antibody

CAT#: TA332669

Rabbit anti-DLD Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using DLD antibody.

• 

  Immunohistochemistry of paraffin-embedded human breast cancer using DLD antibody at dilution of 1:200 (200x lens).

• 

  Immunohistochemistry of paraffin-embedded human esophageal cancer using DLD antibody at dilution of 1:200 (200x lens).

• 

  Immunohistochemistry of paraffin-embedded human stomach using DLD antibody at dilution of 1:200 (200x lens).

• 

  Immunohistochemistry of paraffin-embedded human stomach using DLD antibody at dilution of 1:200 (400x lens).

• 

  Immunohistochemistry of paraffin-embedded mouse lung using DLD antibody at dilution of 1:200 (200x lens).

Show all 6 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human DLD
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 509
• Gene Name: dihydrolipoamide dehydrogenase
• Database Link:
  NP_000099
  Entrez Gene 13382 MouseEntrez Gene 1738 Human
  UniProt ID P09622
• Background: This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
• Synonyms: DLDD; DLDH; E3; GCSL; LAD; PHE3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Citrate cycle (TCA cycle), Glycine, serine and threonine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pyruvate metabolism, Valine, leucine and isoleucine degradation