NPC2 Rabbit Polyclonal Antibody

CAT#: TA332678

Rabbit anti-NPC2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using NPC2 antibody.

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  Immunohistochemistry of paraffin-embedded human kidney using NPC2 antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded human liver cancer using NPC2 antibody at dilution of 1:200 (200x lens).

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  Immunohistochemistry of paraffin-embedded human lung using NPC2 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human NPC2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 151
• Gene Name: NPC intracellular cholesterol transporter 2
• Database Link:
  NP_006423
  Entrez Gene 67963 MouseEntrez Gene 286898 RatEntrez Gene 10577 Human
  UniProt ID P61916
• Background: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
• Synonyms: EDDM1; HE1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein