IRAKM (IRAK3) Rabbit Polyclonal Antibody

CAT#: TA332705

Rabbit anti-IRAK3 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using IRAK3 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human IRAK3
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 596
• Gene Name: interleukin 1 receptor associated kinase 3
• Database Link:
  NP_009130
  Entrez Gene 73914 MouseEntrez Gene 314870 RatEntrez Gene 11213 Human
  UniProt ID Q9Y616
• Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
• Synonyms: ASRT5; IRAKM

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Neurotrophin signaling pathway