Lamin B Receptor (LBR) Rabbit Polyclonal Antibody

CAT#: TA332706

Rabbit anti-LBR Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using LBR antibody.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human LBR
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 615
• Gene Name: lamin B receptor
• Database Link:
  NP_919424
  Entrez Gene 89789 RatEntrez Gene 98386 MouseEntrez Gene 3930 Human
  UniProt ID Q14739
• Background: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
• Synonyms: DHCR14B; LMN2R; PHA; TDRD18

Reference Data

• Protein Families: Druggable Genome, Transmembrane