TXNRD2 Rabbit Polyclonal Antibody

CAT#: TA332723

Rabbit anti-TXNRD2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using TXNRD2 antibody.

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  Immunohistochemical of paraffin-embedded rat kidney using TXNRD2 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human TXNRD2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 524
• Gene Name: thioredoxin reductase 2
• Database Link:
  NP_006431
  Entrez Gene 26462 MouseEntrez Gene 10587 Human
  UniProt ID Q9NNW7
• Background: This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described.
• Synonyms: SELZ; TR; TR-BETA; TR3; TRXR2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Pyrimidine metabolism