NRF1 Rabbit Polyclonal Antibody

CAT#: TA332754

Rabbit anti-NRF1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using NRF1 antibody.

Specifications

Product Data

• Applications: ChIP, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human NRF1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 503
• Gene Name: nuclear respiratory factor 1
• Database Link:
  NP_001035199
  Entrez Gene 18181 MouseEntrez Gene 312195 RatEntrez Gene 4899 Human
  UniProt ID Q16656
• Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
• Synonyms: ALPHA-PAL

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Huntington's disease