RNF2 Rabbit Polyclonal Antibody

CAT#: TA332768

Rabbit anti-RNF2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using RNF2 antibody.

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  Immunohistochemistry of paraffin-embedded human breast cancer using RNF2 antibody at dilution of 1:200 (400x lens).

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  Immunofluorescence analysis of U20S cell using RNF2 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ChIP, ICC/IF, IHC, IP, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200;IP 1:50 - 1:200;ChIP 1:20 - 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human RNF2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 336
• Gene Name: ring finger protein 2
• Database Link:
  NP_009143
  Entrez Gene 19821 MouseEntrez Gene 304850 RatEntrez Gene 6045 Human
  UniProt ID Q99496
• Background: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
• Synonyms: BAP-1; BAP1; DING; HIPI3; RING1B; RING2

Reference Data

• Protein Families: Druggable Genome, Transcription Factors