NFkB p100 / p52 (NFKB2) Rabbit Polyclonal Antibody

CAT#: TA332771

Rabbit anti-NFKB2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using NFKB2 antibody.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:1000;IHC 1:50- 1:100;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human NFKB2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 900
• Gene Name: nuclear factor kappa B subunit 2
• Database Link:
  NP_002493
  Entrez Gene 18034 MouseEntrez Gene 309452 RatEntrez Gene 4791 Human
  UniProt ID Q00653
• Background: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
• Synonyms: CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p52; p100

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: MAPK signaling pathway, Pathways in cancer