CREM Rabbit Polyclonal Antibody

CAT#: TA332796

Rabbit anti-CREM Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CREM antibody.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CREM
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 361
• Gene Name: cAMP responsive element modulator
• Database Link:
  NP_874388
  Entrez Gene 12916 MouseEntrez Gene 25620 RatEntrez Gene 1390 Human
  UniProt ID Q03060
• Background: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
• Synonyms: CREM-2; hCREM-2; ICER

Reference Data

• Protein Families: Druggable Genome, Transcription Factors