Glycerol 3 Phosphate Dehydrogenase (GPD1) Rabbit Polyclonal Antibody

CAT#: TA332859

Rabbit anti-GPD1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various tissues, using GPD1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human GPD1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37 kDa
• Gene Name: glycerol-3-phosphate dehydrogenase 1
• Database Link:
  NP_005267
  Entrez Gene 14555 MouseEntrez Gene 60666 RatEntrez Gene 2819 Human
  UniProt ID P21695
• Background: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: GPD-C; GPDH-C; HTGTI

Reference Data

• Protein Pathways: Glycerophospholipid metabolism