Caspase 2 (CASP2) Rabbit Polyclonal Antibody

CAT#: TA332865

Rabbit anti-CASP2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CASP2 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CASP2
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 452
• Gene Name: caspase 2
• Database Link:
  NP_001215
  Entrez Gene 12366 MouseEntrez Gene 64314 RatEntrez Gene 835 Human
  UniProt ID P42575
• Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57

Reference Data

• Protein Families: Druggable Genome, Protease