Livin (BIRC7) Rabbit Polyclonal Antibody

CAT#: TA332873

Rabbit anti-BIRC7 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using BIRC7 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Mouse, Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human BIRC7
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: baculoviral IAP repeat containing 7
• Database Link:
  NP_647478
  Entrez Gene 329581 MouseEntrez Gene 79444 Human
  UniProt ID Q96CA5
• Background: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
• Synonyms: KIAP; LIVIN; ML-IAP; MLIAP; RNF50

Reference Data

• Protein Families: Druggable Genome