CLCN1 Rabbit Polyclonal Antibody

CAT#: TA332875

Rabbit anti-CLCN1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CLCN1 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CLCN1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 988
• Gene Name: chloride voltage-gated channel 1
• Database Link:
  NP_000074
  Entrez Gene 12723 MouseEntrez Gene 25688 RatEntrez Gene 1180 Human
  UniProt ID P35523
• Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
• Synonyms: CLC1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane