beta 1 Sodium Potassium ATPase (ATP1B1) Rabbit Polyclonal Antibody

CAT#: TA332918

Rabbit anti-ATP1B1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ATP1B1 antibody.

• 

  Immunohistochemistry of paraffin-embedded mouse stomach using ATP1B1 antibody at dilution of 1:100 (x40 lens).

• 

  Immunohistochemistry of paraffin-embedded human liver injury using ATP1B1 antibody at dilution of 1:100 (x40 lens).

• 

  Immunohistochemistry of paraffin-embedded human colon using ATP1B1 antibody at dilution of 1:100 (x40 lens).

• 

  Immunohistochemistry of paraffin-embedded human colon carcinoma using ATP1B1 antibody at dilution of 1:100 (x40 lens).

• 

  Immunohistochemistry of paraffin-embedded human stomach using ATP1B1 antibody at dilution of 1:100 (x40 lens).

• Immunohistochemistry of paraffin-embedded human gastric cancer using ATP1B1 antibody at dilution of 1:100 (x40 lens).

• Immunohistochemistry of paraffin-embedded mouse lung using ATP1B1 antibody at dilution of 1:100 (x40 lens).

Show all 8 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:100 - 1:200
• Reactivities: Mouse, Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ATP1B1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: ATPase Na+/K+ transporting subunit beta 1
• Database Link:
  NP_001001787
  Entrez Gene 11931 MouseEntrez Gene 481 Human
  UniProt ID P05026
• Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
• Synonyms: ATP1B; MGC1798

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cardiac muscle contraction