SETDB1 Rabbit Polyclonal Antibody
USD 867.00
USD 325.00
USD 159.00
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB 1:500 - 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human SETDB1 |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | SET domain bifurcated 1 |
Database Link | |
Background | This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. |
Synonyms | ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Lysine degradation |
Documents
Product Manuals |
FAQs |
SDS |
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