PRMT4 (CARM1) Rabbit Polyclonal Antibody

CAT#: TA333173

Phospho-CARM1-S228 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts from A431 cells using Phospho-CARM1-S228 antibody.

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  Immunofluorescence staining of methanol- fixed HeLa cells using Phospho-CARM1-S228 antibody.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB 1:500-1:2000, IF 1:100-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A phospho specific peptide corresponding to residues surrounding S228 of human CARM1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 608
• Gene Name: coactivator associated arginine methyltransferase 1
• Database Link:
  NP_954592
  Entrez Gene 59035 MouseEntrez Gene 363026 RatEntrez Gene 10498 Human
  UniProt ID Q86X55
• Background: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.
• Synonyms: PRMT4

Reference Data

• Protein Families: Druggable Genome, Transcription Factors