CDK2 Rabbit Polyclonal Antibody

CAT#: TA333179

Phospho-CDK2-T160 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts from Hela cells using Phospho-CDK2-T160 antibody.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB,1:100 - 1:500
  IHC-P,1:50 - 1:100
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34kDa
• Gene Name: cyclin-dependent kinase 2
• Database Link:
  NP_439892
  Entrez Gene 12566 MouseEntrez Gene 362817 RatEntrez Gene 1017 Human
  UniProt ID P24941
• Background: This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.
• Synonyms: CDKN2; p33(CDK2)

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Small cell lung cancer