c Rel (REL) Rabbit Polyclonal Antibody

CAT#: TA333288

Phospho-REL-S503 Rabbit Polyclonal Antibody

Product Images

Immunofluorescence staining of methanol-fixed Hela cells, using Phospho-REL-S503 antibody.

Specifications

Product Data

• Applications: IF
• Recommended Dilution: IF 1:100-1:200
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A phospho specific peptide corresponding to residues surrounding S503 of human REL
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 619
• Gene Name: REL proto-oncogene, NF-kB subunit
• Database Link:
  NP_002899
  Entrez Gene 5966 Human
  UniProt ID Q04864
• Background: The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007
• Synonyms: C-Rel

Reference Data

• Protein Families: Druggable Genome, Transcription Factors