OATP2 (SLCO1B1) Rabbit Polyclonal Antibody

CAT#: TA333919

Rabbit Polyclonal Anti-SLCO1B1 Antibody

Product Images

WB Suggested Anti-SLCO1B1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: HepG2 cell lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-SLCO1B1 Antibody: synthetic peptide directed towards the middle region of human SLCO1B1. Synthetic peptide located within the following region: IILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETH
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 76 kDa
• Gene Name: solute carrier organic anion transporter family member 1B1
• Database Link:
  NP_006437
  Entrez Gene 10599 Human
  UniProt ID Q9Y6L6
• Background: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
• Synonyms: HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2; OATPC; SLC21A6
• Note: Immunogen sequence homology: Human: 100%; Bovine: 86%; Pig: 79%

Reference Data

• Protein Families: Druggable Genome, Transmembrane