Bile Acid Receptor (NR1H4) Rabbit Polyclonal Antibody

CAT#: TA334218

Rabbit Polyclonal Anti-NR1H4 Antibody

Product Images

WB Suggested Anti-NR1H4 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Lung

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  WB Suggested Anti-NR1H4 Antibody ; Positive Control: Lane 1: 50ug mouse glomerular endothelial lysate; Primary Antibody Dilution : 1:1000; Secondary Antibody : Anti-rabbit-HRP; Secondry Antibody Dilution : 1:5000; Submitted by: Xiaoxin Wang, UC Denver

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  Human kidney

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-NR1H4 antibody: synthetic peptide directed towards the middle region of human NR1H4. Synthetic peptide located within the following region: AECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTTKSCREKT
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: nuclear receptor subfamily 1 group H member 4
• Database Link:
  NP_005114
  Entrez Gene 20186 MouseEntrez Gene 9971 Human
  UniProt ID Q96RI1
• Background: The NR1H4 gene encodes a protein that has a central role in lipid homeostasis and also regulates carbohydrate metabolism.
• Synonyms: BAR; FXR; HRR-1; HRR1; PFIC5; RIP14
• Note: Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Guinea pig: 100%; Rabbit: 93%

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors