CCR1 Rabbit Polyclonal Antibody

CAT#: TA336335

Rabbit Polyclonal CCR1 Antibody


USD 424.00

2 Weeks*

Size
    • 100 ug

Product Images

Frequently bought together (2)
Transient overexpression lysate of chemokine (C-C motif) receptor 1 (CCR1)
    • 100 ug

USD 396.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Other products for "CCR1"

Specifications

Product Data
Applications FC, IHC, WB
Recommended Dilution Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Flow (Cell Surface), Flow (Intracellular), Immunohistochemistry-Frozen, Flow Cytometry: 5-10 ul/test, Western Blot: 1-3 ug/ml, Immunohistochemistry-Paraffin: 5 ug/ml
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen This antibody was raised against a synthetic peptide of human CCR1 protein.
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name C-C motif chemokine receptor 1
Background Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines (2-4). Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation (5,6).
Synonyms CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.