SIRT7 Rabbit Polyclonal Antibody

CAT#: TA336342

Rabbit Polyclonal SIRT7 Antibody


USD 402.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications WB
Recommended Dilution Western Blot: 1-3 ug/ml
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen A mixture of synthetic peptides corresponding to amino acids 35-51 and 361-377 of human SIRT7 was used as immunogen.
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name sirtuin 7
Background SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Synonyms SIR2L7
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.