IL20 Receptor alpha (IL20RA) Rabbit Polyclonal Antibody

CAT#: TA336352

Rabbit Polyclonal IL-20 R alpha Antibody

Product Images

Flow Cytometry: IL-20 R alpha Antibody TA336352 - Cell-surface flow cytometry analysis of IL-20 R alpha Antibodyin A375 cells using this antibody at 5 ug/10^6 cells. The shaded histogram represents cells only, green represents isotype control, and purple represents anti-IL-20 R alpha Antibody

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  Western Blot: IL-20 R alpha Antibody TA336352 - Analysis of IL-20 R alpha Antibody in A375 cell lysate in the (A) absence and (B) presence of blocking peptide using this antibody at 2 ug/ml.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: Western Blot: 1-3 ug/ml, Flow Cytometry: 2-5 ug/10^6 cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Amino acids 159-175 of human IL-20 receptor alpha protein were used as the immunogen.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 20 receptor subunit alpha
• Database Link:
  NP_055247
  Entrez Gene 237313 MouseEntrez Gene 53832 Human
  UniProt ID Q9UHF4
• Background: Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.
• Synonyms: CRF2-8; IL-20R-alpha; IL-20R1; IL-20RA

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway