VDAC2 Rabbit Polyclonal Antibody

CAT#: TA336364

Rabbit Polyclonal VDAC2/3 Antibody

Product Images

Western Blot: VDAC2/3 Antibody TA336364 - analysis of VDAC2/3 in human brain cell lysate in the A) absence and B) presence of immunizing peptide using this antibody. The approximately 55 kD band is not blocked by the immunizing peptide and is believed to result from non-specific cross-reaction.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1-3 ug/ml
• Reactivities: Human, Bovine, Canine, Feline, Primate
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Amino acids 120-132 (KKSGKIKSSYKRE) of human VDAC2 protein were used as the immunogen.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: voltage dependent anion channel 2
• Database Link:
  NP_003366
  Entrez Gene 7417 Human
  UniProt ID P45880
• Background: Voltage-dependent anion channels (VDAC) are small pore-forming membrane proteins that regulate metabolite exchange across the mitochondrial outer membrane. Apart from metabolite transfer, VDAC role has also been suggested during apoptosis. VDAC2 is one of the isoforms of VDAC. It interacts with BAK and functions as a specific inhibitor of BAK-dependent mitochondrial apoptosis.
• Synonyms: POR

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Calcium signaling pathway, Huntington's disease, Parkinson's disease