ATF2 Mouse Monoclonal Antibody [Clone ID: 103C411.2]

CAT#: TA336422

Mouse Monoclonal ATF2 [p Thr71] Antibody (103C411.2)


USD 424.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Clone Name 103C411.2
Applications FC
Recommended Dilution Flow Cytometry: 1:10-1:1000, Western Blot: 2 ug/ml
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen This antibody was generated by immunizing mice with a synthetic peptide containing phosphorylated threonine at position 71 of human ATF-2.
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name activating transcription factor 2
Background ATF-2 is a member of the group of bZip transcription factors. Heterodimer formation between members of the bZip group is common and is believed to add diversity to the cis-acting elements at which binding of the dimers is directed. Specifically, ATF-2 may dimerize with c-Jun, as occurs in response to E1a, and in so doing shift the binding preference of c-Jun toward ATF/CRE sites. Deletion analysis has indicated that the N-terminal region of ATF-2 containing threonine at residues 69 and 71 are essential for this purpose. These threonine residues are phosphorylated by JNK/SAPK for transcriptional activation.
Synonyms CRE-BP1; CREB-2; CREB2; HB16; TREB7
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways MAPK signaling pathway

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