SMAD1 Rabbit Polyclonal Antibody

CAT#: TA336440

Rabbit Polyclonal SMAD1/5/8/9 Antibody

Product Images

Western Blot: SMAD1/5/8/9 Antibody TA336440 - Analysis using SMAD1/5/8/9 antibody. Lysate from Saos-2 cells probed with SMAD antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: This antibody was developed against two synthetic peptides corresponding to amino acids 19-33 (GWKQGDEEEKWAEKA) and amino acids 315-329 (SNVNRNSTIENTRRH) of human SMAD1.
• Formulation: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Whole antisera
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SMAD family member 1
• Database Link:
  NP_005891
  Entrez Gene 17125 MouseEntrez Gene 25671 RatEntrez Gene 4086 Human
  UniProt ID Q15797
• Background: SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily (1). SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them.
• Synonyms: BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1

Reference Data

• Protein Families: Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
• Protein Pathways: TGF-beta signaling pathway