Presenilin 1 (PSEN1) Rabbit Polyclonal Antibody

CAT#: TA336586

Rabbit Polyclonal Presenilin-1 Antibody

Product Images

Western Blot: Presenilin 1 Antibody TA336586 - Analysis of Human Presenilin 1 / PSDR1 in androgen-stimulated metastatic adenocarcinoma LNCaP.FGC cells with Presenilin 1 antibody at a dilution of 1:500

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: , ELISA: 1:100-1:2000, IHC: 1:10-1:500, IHC-F: 1:10-1:500, IHC-P: 1:10-1:500, IP: 1:10-1:500
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptides corresponding to the N terminal sequence MVELMFP and the C terminal sequence LLGLPID of the human Presenilin 1 protein.
• Formulation: PBS, 0.02% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: presenilin 1
• Database Link:
  NP_000012
  Entrez Gene 5663 Human
  UniProt ID P49768
• Background: Presenilin 1 is a novel prostate short-chain dehydrogenase/reductase that exhibits increased expression on exposure to androgens in the LNCaP prostate cancer cell line. Presenilin 1 is expressed in normal and neoplastic prostate epithelium and is implicated in the pathogenesis of prostate carcinoma.
• Synonyms: AD3; FAD; PS-1; PS1; S182
• Note: This Presenilin 1 antibody is useful for Immunoprecipitation, Immunohistochemistry frozen and paraffin embedded sections and ELISA.

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane
• Protein Pathways: Alzheimer's disease, Neurotrophin signaling pathway, Notch signaling pathway, Wnt signaling pathway