Prostate Specific Antigen (KLK3) Rabbit Polyclonal Antibody

CAT#: TA336588

Rabbit Polyclonal Kallikrein 3/PSA Antibody

Product Images

Western Blot: Prostate Specific Antigen Antibody TA336588 - Analysis of Prostate Specific Antigen (PSA / KLK3) in LNCaP cells using this antibody at a dilution of 1:1000

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:100-1:2000, ELISA: 1:100-1:2000, IHC: 1:10-1:500, IHC-F: 1:10-1:500, IHC-P: 1:10-1:500, IP: 1:10-1:500
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Residues 247-261 [VHYRKWIKDTIVANP] of the human KLK 3 protein
• Formulation: PBS, 0.02% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: kallikrein related peptidase 3
• Database Link:
  NP_001639
  Entrez Gene 354 Human
  UniProt ID P07288
• Background: Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. KLK 3 (also known as prostate specific antigen) is a marker for prostatic cancer and is involved in the pathogenesis and/or progression of prostate, breast, and possibly other malignancies. PSA is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum levels of this protein are useful in the diagnosis and monitoring of prostatic carcinoma
• Synonyms: APS; hK3; KLK2A1; PSA
• Note: Western blot

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Pathways in cancer, Prostate cancer