Caspase 10 (CASP10) Rabbit Polyclonal Antibody

CAT#: TA336663

Rabbit Polyclonal Caspase-10/FLICE2 Antibody

Product Images

Western Blot: Caspase 10 Antibody TA336663 - WB detection of Caspase-10 in Jurkat cells using TA336663 at a dilution of 1:500. Before making the lysates, the cells were treated with 2 uM staurosporine for different time periods as shown in the image.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:100-1:2000
• Reactivities: Chicken, Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to N-terminus of Human Caspase 10
• Formulation: PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: caspase 10
• Database Link:
  NP_001193453
  Entrez Gene 843 Human
  UniProt ID Q92851
• Background: Caspases are death effector domain-containing cysteine aspartases presumed to be at or near the apex of apoptotic signaling pathways. All known isoforms of caspase-10 are abundantly expressed in fetal lung, kidney, and skeletal muscle but are very poorly expressed or absent in these tissues in the adult, implying a possible role for the caspase-10 family in fetal development.
• Synonyms: ALPS2; FLICE2; MCH4
• Note: Western blot- Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application.

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Apoptosis, RIG-I-like receptor signaling pathway