Kv1.2 (KCNA2) Rabbit Polyclonal Antibody

CAT#: TA336756

Rabbit Polyclonal Kv1 Antibody

Product Images

Western Blot: Kv1 Antibody TA336756 - Membrane preparations from HEK-293 cells untransfected (lane 1) transfected with Kv1.2 (lanes 2 and 4) and transfected with Kv1.3 (lane 3) were subjected to 10% SDS-PAGE and were Western blotted with Kv1 Antibody (T

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:1000, IP: 1:10-1:500
• Reactivities: Human, Mouse, Rat, Bovine, Canine, Porcine, Xenopu
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide made to rat Kv1.2 (within residues 50-100), which is identical in all members of the Kv1 family.
• Formulation: PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: potassium voltage-gated channel subfamily A member 2
• Database Link:
  NP_004965
  Entrez Gene 16490 MouseEntrez Gene 25468 RatEntrez Gene 3737 Human
  UniProt ID P16389
• Background: Kv1 is a subfamily (also called the Shaker family) of voltage-gated potassium channels containing at least seven members. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The Kv1 subfamily may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.
• Synonyms: EIEE32; HBK5; HK4; HUKIV; KV1.2; MK2; NGK1; RBK2
• Note: This Kv1 antibody is useful for Immunoprecipitation and Western blot, where a band can be seen at ~80 kDa.

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane