Synaptophysin (SYP) Mouse Monoclonal Antibody [Clone ID: 7H12]

CAT#: TA336774

Mouse Monoclonal Synaptophysin Antibody (7H12)

Product Images

Immunohistochemistry-Paraffin: Synaptophysin Antibody (7H12) TA336774 - Analysis of paraffin-embedded human small intestine, myenteric plexus tissues using anti-Synaptophysin mouse mAb.

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  Western Blot: Synaptophysin Antibody (7H12) TA336774 - Analysis using Synaptophysin mouse mAb against rat brain tissue lysate.

Specifications

Product Data

• Clone Name: 7H12
• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:10000, Immunohistochemistry, Western Blot: 1:500 - 1:2000, Immunohistochemistry-Paraffin: 1:200 - 1:1000
• Reactivities: Human, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human Synaptophysin expressed in E. coli. [UniProt# P08247]
• Formulation: Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33.8 kDa
• Gene Name: synaptophysin
• Database Link:
  NP_003170
  Entrez Gene 24804 RatEntrez Gene 6855 Human
  UniProt ID P08247
• Background: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.
• Synonyms: MRX96; MRXSYP
• Note: This Synaptophysin (7H12) antibody is useful in Western Blot, ELISA, and Immunohistochemistry on paraffin-embedded sections.

Reference Data

• Protein Families: Secreted Protein, Transmembrane